DelveInsight’s, “Advanced Urothelial Carcinoma Pipeline Insight 2025” report provides comprehensive insights about 25+ companies and 30+ pipeline drugs in Advanced Urothelial Carcinoma pipeline landscape. It covers the Advanced Urothelial Carcinoma pipeline drug profiles, including clinical and nonclinical stage products. It also covers the Advanced Urothelial Carcinoma therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

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Key Takeaways from the Advanced Urothelial Carcinoma Pipeline Report

• In April 2025, Janssen Research & Development LLC conducted a study is to: (a) characterize the safety and tolerability of and to identify the recommended Phase 2 dose (RP2D) and schedule for erdafitinib in combination with cetrelimab, and for erdafitinib in combination with cetrelimab and platinum (cisplatin and carboplatin) chemotherapy and; (b) to evaluate the safety and clinical activity of erdafitinib alone and in combination with cetrelimab in cisplatin-ineligible participants with metastatic or locally advanced urothelial cancer (UC) with select fibroblast growth factor receptor (FGFR) gene alterations and no prior systemic therapy for metastatic disease.
• DelveInsight’s Advanced Urothelial Carcinoma pipeline report depicts a robust space with 25+ active players working to develop 30+ pipeline therapies for Advanced Urothelial Carcinoma treatment.
• The leading Advanced Urothelial Carcinoma Companies such as Merck Sharp & Dohme LLC, Evopoint Biosciences Inc., Exelixis, Tyra Biosciences, Inc., BeiGene, BicycleTx Limited, Bristol-Myers Squibb, Sichuan Baili Pharmaceutical Co., Ltd., Nektar Therapeutics, Bayer, Abbisko Therapeutics Co., Ltd., Aurigene Discovery Technologies Limited, Adlai Nortye Biopharma Co., Ltd., Mabwell (Shanghai) Bioscience Co., Ltd. and others.
• Promising Advanced Urothelial Carcinoma Pipeline Therapies such as SHR-A2102, Adebrelimab injection, Selinexor, Pembrolizumab, 9MW2821, Toripalimab and others.

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Advanced Urothelial Carcinoma Emerging Drugs Profile

• 9MW2821: Mabwell (Shanghai) Bioscience Co., Ltd.

9MW2821 is a novel Nectin-4 targeting ADC developed by ADC platform and automated high-throughput antibody discovery platform of Mabwell. It boasts the advantages of homogenous structure, high purity and being easy production. It has also demonstrated favorable druggability properties in binding affinity, endocytosis, preliminary in vivo and in vitro pharmacodynamic activities, drug metabolism properties and preliminary safety. Currently, the drug is in Phase III stage of its clinical trial for the treatment of Advanced Urothelial Carcinoma.

• AZD4547: Abbisko Therapeutics Co, Ltd

AZD-4547 is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with potential antineoplastic activity. FGFR inhibitor AZD4547 binds to and inhibits FGFR, which may result in the inhibition of FGFR-related signal transduction pathways, and, so, the inhibition of tumor cell proliferation and tumor cell death. Currently, the drug is in Phase II stage of its clinical trial for the treatment of Advanced Urothelial Carcinoma.

• AUR106: Aurigene Discovery Technologies Limited

AUR106 is an orally bioavailable small molecule inhibitor of the co-inhibitory molecule and immune checkpoint inhibitor T-cell immunoreceptor with immunoglobulin (Ig) and immunoreceptor tyrosine-based inhibitory motif (ITIM) domains (TIGIT) and the immunosuppressive ligand programmed cell death-1 ligand 1, with potential immune checkpoint inhibitory and antineoplastic activities. Upon oral administration, TIGIT/PD-L1 inhibitor AUR-106 simultaneously targets, binds to and inhibits TIGIT and PD-L1, thereby inhibiting their downstream signaling pathways. Currently, the drug is in Phase I stage of its clinical trial for the treatment of Advanced Urothelial Carcinoma.

The Advanced Urothelial Carcinoma Pipeline Report Provides Insights into

• The report provides detailed insights about companies that are developing therapies for the treatment of Advanced Urothelial Carcinoma with aggregate therapies developed by each company for the same.
• It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Advanced Urothelial Carcinoma Treatment.
• Advanced Urothelial Carcinoma Companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
• Advanced Urothelial Carcinoma Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.
• Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Advanced Urothelial Carcinoma market

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Advanced Urothelial Carcinoma Companies

Merck Sharp & Dohme LLC, Evopoint Biosciences Inc., Exelixis, Tyra Biosciences, Inc., BeiGene, BicycleTx Limited, Bristol-Myers Squibb, Sichuan Baili Pharmaceutical Co., Ltd., Nektar Therapeutics, Bayer, Abbisko Therapeutics Co., Ltd., Aurigene Discovery Technologies Limited, Adlai Nortye Biopharma Co., Ltd., Mabwell (Shanghai) Bioscience Co., Ltd. and others.

Advanced Urothelial Carcinoma pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as

• Oral
• Intravenous
• Subcutaneous
• Parenteral
• Topical

Advanced Urothelial Carcinoma Products have been categorized under various Molecule types such as

• Monoclonal Antibody
• Peptides
• Polymer
• Small molecule
• Gene therapy

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Scope of the Advanced Urothelial Carcinoma Pipeline Report

• Coverage- Global
• Advanced Urothelial Carcinoma Companies- Merck Sharp & Dohme LLC, Evopoint Biosciences Inc., Exelixis, Tyra Biosciences, Inc., BeiGene, BicycleTx Limited, Bristol-Myers Squibb, Sichuan Baili Pharmaceutical Co., Ltd., Nektar Therapeutics, Bayer, Abbisko Therapeutics Co., Ltd., Aurigene Discovery Technologies Limited, Adlai Nortye Biopharma Co., Ltd., Mabwell (Shanghai) Bioscience Co., Ltd. and others.
• Advanced Urothelial Carcinoma Pipeline Therapies- SHR-A2102, Adebrelimab injection, Selinexor, Pembrolizumab, 9MW2821, Toripalimab and others.
• Advanced Urothelial Carcinoma Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination
• Advanced Urothelial Carcinoma Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III

Get the latest on Advanced Urothelial Carcinoma Therapies and clinical trials. Download DelveInsight’s in-depth pipeline report today! @ Advanced Urothelial Carcinoma Companies, Key Products and Unmet Needs

Table of Content

1. Introduction
2. Executive Summary
3. Advanced Urothelial Carcinoma: Overview
4. Pipeline Therapeutics
5. Therapeutic Assessment
6. Advanced Urothelial Carcinoma – DelveInsight’s Analytical Perspective
7. Late Stage Products (Phase III)
8. 9MW2821: Mabwell (Shanghai) Bioscience Co., Ltd.
9. Drug profiles in the detailed report…..
10. Mid Stage Products (Phase II)
11. AZD4547: Abbisko Therapeutics Co, Ltd
12. Drug profiles in the detailed report…..
13. Early Stage Products (Phase I)
14. AUR106: Aurigene Discovery Technologies Limited
15. Drug profiles in the detailed report…..
16. Preclinical and Discovery Stage Products
17. Drug name: Company name
18. Drug profiles in the detailed report…..
19. Inactive Products
20. Advanced Urothelial Carcinoma Key Companies
21. Advanced Urothelial Carcinoma Key Products
22. Advanced Urothelial Carcinoma- Unmet Needs
23. Advanced Urothelial Carcinoma- Market Drivers and Barriers
24. Advanced Urothelial Carcinoma- Future Perspectives and Conclusion
25. Advanced Urothelial Carcinoma Analyst Views
26. Advanced Urothelial Carcinoma Key Companies
27. Appendix

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