“Chronic Rhinosinusitis Pipeline Insight, 2024“ report by DelveInsight outlines comprehensive insights into the present clinical development scenario and growth prospects across the Chronic Rhinosinusitis Market.
The Chronic Rhinosinusitis Pipeline report embraces in-depth commercial and clinical assessment of the pipeline products from the pre-clinical developmental phase to the marketed phase. The report also covers a detailed description of the drug, including the mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, collaborations, mergers acquisition, funding, designations, and other product-related details.
Some of the key takeaways from the Chronic Rhinosinusitis Pipeline Report:
Companies across the globe are diligently working toward developing novel Chronic Rhinosinusitis treatment therapies with a considerable amount of success over the years.
Chronic Rhinosinusitis companies working in the treatment market are Lanier Biotherapeutics, Trellis Bioscience, Insmed Incorporated, Biohaven Pharmaceuticals, Regeneron Pharmaceuticals, Lyra Therapeutics, and others, are developing therapies for the Chronic Rhinosinusitis treatment
Emerging Chronic Rhinosinusitis therapies in the different phases of clinical trials are- LNR 125.38, TRL1068, Brensocatib, Rimegepant, Dupilumab, LYR-210, and others are expected to have a significant impact on the Chronic Rhinosinusitis market in the coming years.
In November 2024, Amgen (NASDAQ: AMGN) and AstraZeneca have announced positive top-line results from the Phase 3 WAYPOINT trial evaluating TEZSPIRE® (tezepelumab-ekko) in patients with chronic rhinosinusitis with nasal polyps (CRSwNP). The study showed that patients treated with TEZSPIRE experienced a statistically significant and clinically meaningful reduction in nasal polyp size and improvement in nasal congestion compared to placebo. Additionally, the safety and tolerability profile of TEZSPIRE in the trial remained consistent with its known safety profile.
In October 2024, UK-based pharmaceutical company GSK has reported positive results from the Phase III ANCHOR-1 and ANCHOR-2 clinical trials evaluating depemokimab in adults with chronic rhinosinusitis with nasal polyps (CRSwNP). The full analysis included 143 patients receiving depemokimab and 128 on placebo in ANCHOR-1, while ANCHOR-2 comprised 129 patients treated with depemokimab and 128 receiving placebo.
In January 2024, Upstream Bio commenced dosing the initial participants in a Phase II clinical study for its monoclonal antibody, verekitug, designed for the treatment of chronic rhinosinusitis with nasal polyps (CRSwNP).
In January 2024, Insmed expects to release key findings from the Phase 2b BiRCh trial evaluating brensocatib in patients with Chronic Rhinosinusitis without nasal polyps (CRSsNP) in the year 2025.
In January 2024, GSK plc (LSE/NYSE: GSK) has received approval from the China National Medical Products Administration for Nucala (mepolizumab) as an additional maintenance therapy for severe eosinophilic asthma in adults and adolescents aged 12 years and older. This marks the first approval in China for the use of Nucala, an anti-Interleukin-5 (IL-5) targeting treatment, in adult and adolescent patients with this condition. Previously approved in China for use in adults with EGPA, Nucala was added to the National Reimbursement Drug List in January 2023. Having undergone extensive study across multiple IL-5 mediated conditions, Nucala was the inaugural treatment approved in the US and Europe for four IL-5 mediated conditions, including severe asthma with an eosinophilic phenotype, EGPA, hypereosinophilic syndrome, and chronic rhinosinusitis with nasal polyps. Additionally, Nucala has secured approval in the US, the European Union, and more than 25 other markets as an adjunctive maintenance treatment for severe asthma patients.
Chronic Rhinosinusitis Overview
Chronic Rhinosinusitis (CRS) is a long-term inflammation of the nasal and sinus passages that lasts for more than 12 weeks. It is a common condition that can significantly impact a person’s quality of life. CRS is characterized by inflammation of the mucous membranes lining the nose and sinuses, leading to symptoms such as nasal congestion, facial pain or pressure, and difficulty breathing through the nose.
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Emerging Chronic Rhinosinusitis Drugs Under Different Phases of Clinical Development Include:
LNR 125.38: Lanier Biotherapeutics
TRL1068: Trellis Bioscience
Brensocatib: Insmed Incorporated
Rimegepant: Biohaven Pharmaceuticals
Dupilumab: Regeneron Pharmaceuticals
LYR-210: Lyra Therapeutics
Chronic Rhinosinusitis Route of Administration
Chronic Rhinosinusitis pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs, such as
Oral
Parenteral
Intravitreal
Subretinal
Topical
Molecule Type
Chronic Rhinosinusitis Molecule Type
Chronic Rhinosinusitis Products have been categorized under various Molecule types, such as
Monoclonal Antibody
Peptides
Polymer
Small molecule
Gene therapy
Product Type
Chronic Rhinosinusitis Pipeline Therapeutics Assessment
Chronic Rhinosinusitis Assessment by Product Type
Chronic Rhinosinusitis By Stage and Product Type
Chronic Rhinosinusitis Assessment by Route of Administration
Chronic Rhinosinusitis By Stage and Route of Administration
Chronic Rhinosinusitis Assessment by Molecule Type
Chronic Rhinosinusitis by Stage and Molecule Type
DelveInsight’s Chronic Rhinosinusitis Report covers around 6+ products under different phases of clinical development like
Late-stage products (Phase III)
Mid-stage products (Phase II)
Early-stage product (Phase I)
Pre-clinical and Discovery stage candidates
Discontinued & Inactive candidates
Route of Administration
Further Chronic Rhinosinusitis product details are provided in the report. Download the Chronic Rhinosinusitis pipeline report to learn more about the emerging Chronic Rhinosinusitis therapies
Some of the key companies in the Chronic Rhinosinusitis Therapeutics Market include:
Key companies developing therapies for Chronic Rhinosinusitis are – AstraZeneca, Amgen, GlaxoSmithKline, Keymed Biosciences, Biohaven Pharmaceuticals, and others.
Chronic Rhinosinusitis Pipeline Analysis:
The Chronic Rhinosinusitis pipeline report provides insights into
The report provides detailed insights about companies that are developing therapies for the treatment of Chronic Rhinosinusitis with aggregate therapies developed by each company for the same.
It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Chronic Rhinosinusitis Treatment.
Chronic Rhinosinusitis key companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
Chronic Rhinosinusitis Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.
Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Chronic Rhinosinusitis market.
The report is built using data and information traced from the researcher’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations, and featured press releases from company/university websites and industry-specific third-party sources, etc.
Download Sample PDF Report to know more about Chronic Rhinosinusitis drugs and therapies
Chronic Rhinosinusitis Pipeline Market Drivers
Increasing demand for minimally invasive techniques, increasing awareness about the target disease and treatment are some of the important factors that are fueling the Chronic Rhinosinusitis Market.
Chronic Rhinosinusitis Pipeline Market Barriers
However, time-consuming clinical trials, unknown cause of chronic Rhinosinusitis and other factors are creating obstacles in the Chronic Rhinosinusitis Market growth.
Scope of Chronic Rhinosinusitis Pipeline Drug Insight
Coverage: Global
Key Chronic Rhinosinusitis Companies: Lanier Biotherapeutics, Trellis Bioscience, Insmed Incorporated, Biohaven Pharmaceuticals, Regeneron Pharmaceuticals, Lyra Therapeutics, and others
Key Chronic Rhinosinusitis Therapies: LNR 125.38, TRL1068, Brensocatib, Rimegepant, Dupilumab, LYR-210, and others
Chronic Rhinosinusitis Therapeutic Assessment: Chronic Rhinosinusitis current marketed and Chronic Rhinosinusitis emerging therapies
Chronic Rhinosinusitis Market Dynamics: Chronic Rhinosinusitis market drivers and Chronic Rhinosinusitis market barriers
Request for Sample PDF Report for Chronic Rhinosinusitis Pipeline Assessment and clinical trials
Table of Contents
1. Chronic Rhinosinusitis Report Introduction
2. Chronic Rhinosinusitis Executive Summary
3. Chronic Rhinosinusitis Overview
4. Chronic Rhinosinusitis- Analytical Perspective In-depth Commercial Assessment
5. Chronic Rhinosinusitis Pipeline Therapeutics
6. Chronic Rhinosinusitis Late Stage Products (Phase II/III)
7. Chronic Rhinosinusitis Mid Stage Products (Phase II)
8. Chronic Rhinosinusitis Early Stage Products (Phase I)
9. Chronic Rhinosinusitis Preclinical Stage Products
10. Chronic Rhinosinusitis Therapeutics Assessment
11. Chronic Rhinosinusitis Inactive Products
12. Company-University Collaborations (Licensing/Partnering) Analysis
13. Chronic Rhinosinusitis Key Companies
14. Chronic Rhinosinusitis Key Products
15. Chronic Rhinosinusitis Unmet Needs
16 . Chronic Rhinosinusitis Market Drivers and Barriers
17. Chronic Rhinosinusitis Future Perspectives and Conclusion
18. Chronic Rhinosinusitis Analyst Views
19. Appendix
20. About DelveInsight
About DelveInsight
DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance. It also offers Healthcare Consulting Services, which benefits in market analysis to accelerate business growth and overcome challenges with a practical approach.
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