“Mesothelioma Pipeline Insight, 2024“ report by DelveInsight outlines comprehensive insights into the present clinical development scenario and growth prospects across the Mesothelioma Market.
The Mesothelioma Pipeline report embraces in-depth commercial and clinical assessment of the pipeline products from the pre-clinical developmental phase to the marketed phase. The report also covers a detailed description of the drug, including the mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, collaborations, mergers acquisition, funding, designations, and other product-related details.
Some of the key takeaways from the Mesothelioma Pipeline Report:
Companies across the globe are diligently working toward developing novel Mesothelioma treatment therapies with a considerable amount of success over the years.
Mesothelioma companies working in the treatment market are The Netherlands Cancer Institute, Bristol-Myers Squibb, PrECOG, LLC., Memorial Sloan Kettering Cancer Center, ETOP IBCSG Partners Foundation, MedImmune LLC, Åslaug Helland, AstraZeneca, Oncotelic Inc., Hyogo Medical University, Trizell Ltd, RS Oncology LLC, Vivace Therapeutics, Inc, TCR2 Therapeutics, Sanofi, ImmVira Pharma Co. Ltd, TCR2 Therapeutics, CRISPR Therapeutics, Biotheus Inc., and others, are developing therapies for the Mesothelioma treatment
Emerging Mesothelioma therapies in the different phases of clinical trials are- Pembrolizumab, Nivolumab, Durvalumab, Sacituzumab govitecan-hziy, Carboplatin, Tremelimumab, ipilimumab, Volrustomig, OT-101, Lenvatinib, rAd-IFN, RSO-021, VT3989, gavo-cel, THOR-707, T3011, TC-510, CTX131, PM8002, and others are expected to have a significant impact on the Mesothelioma market in the coming years.
In January 2025, Insilico Medicine (“Insilico”), a clinical-stage AI-driven biotechnology company, has announced that the first patient has been dosed in its global multicenter Phase I trial of ISM6331, a novel pan-TEAD inhibitor developed using its AI-powered generative chemistry platform, Chemistry42. ISM6331 is being investigated for the treatment of mesothelioma and other solid tumors. Notably, it is Insilico’s leading oncology program within its AI-driven drug discovery pipeline and has received Orphan Drug Designation (ODD) from the FDA for mesothelioma treatment.
In September 2024, The FDA approved Keytruda (pembrolizumab) as a first-line treatment for unresectable advanced or metastatic malignant pleural mesothelioma (MPM). Keytruda, an immunotherapy drug, enhances the immune system’s ability to identify and eliminate cancer cells by inhibiting specific proteins in immune cells, improving their effectiveness in targeting cancer. This approval offers new hope for individuals diagnosed with malignant pleural mesothelioma, the most prevalent form of the disease, accounting for approximately 75% of cases.
In March 2024, Ultimovacs, a clinical-stage biotechnology company, released data from the Phase II NIPU trial of its UV1 cancer vaccine. This investigator-initiated, open-label, multi-center Phase II trial evaluated the impact of incorporating the UV1 cancer vaccine into second-line treatment with ipilimumab and nivolumab for patients with pleural mesothelioma.
Mesothelioma Overview
Mesothelioma is a type of cancer that develops from the thin layer of tissue that covers many of the internal organs (mesothelium). The most common form is pleural mesothelioma, which affects the lining of the lungs and is often associated with exposure to asbestos fibers. Other less common forms include peritoneal mesothelioma (affecting the lining of the abdomen), pericardial mesothelioma (affecting the lining around the heart), and mesothelioma of the tunica vaginalis (affecting the lining of the testes).
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Emerging Mesothelioma Drugs Under Different Phases of Clinical Development Include:
Pembrolizumab: The Netherlands Cancer Institute
Nivolumab: Bristol-Myers Squibb
Durvalumab: PrECOG, LLC.
Sacituzumab govitecan-hziy: Memorial Sloan Kettering Cancer Center
Carboplatin: ETOP IBCSG Partners Foundation
Tremelimumab: MedImmune LLC
ipilimumab: Åslaug Helland
Volrustomig: AstraZeneca
OT-101: Oncotelic Inc.
Lenvatinib: Hyogo Medical University
rAd-IFN: Trizell Ltd
RSO-021: RS Oncology LLC
VT3989: Vivace Therapeutics, Inc
gavo-cel: TCR2 Therapeutics
THOR-707: Sanofi
T3011: ImmVira Pharma Co. Ltd
TC-510: TCR2 Therapeutics
CTX131: CRISPR Therapeutics
PM8002: Biotheus Inc.
Mesothelioma Route of Administration
Mesothelioma pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs, such as
Oral
Parenteral
Intravenous
Subcutaneous
Topical
Mesothelioma Molecule Type
Mesothelioma Products have been categorized under various Molecule types, such as
Recombinant fusion proteins
Small molecule
Monoclonal antibody
Peptide
Polymer
Gene therapy
Mesothelioma Pipeline Therapeutics Assessment
Mesothelioma Assessment by Product Type
Mesothelioma By Stage and Product Type
Mesothelioma Assessment by Route of Administration
Mesothelioma By Stage and Route of Administration
Mesothelioma Assessment by Molecule Type
Mesothelioma by Stage and Molecule Type
DelveInsight’s Mesothelioma Report covers around 50+ products under different phases of clinical development like
Late-stage products (Phase III)
Mid-stage products (Phase II)
Early-stage product (Phase I)
Pre-clinical and Discovery stage candidates
Discontinued & Inactive candidates
Route of Administration
Further Mesothelioma product details are provided in the report. Download the Mesothelioma pipeline report to learn more about the emerging Mesothelioma therapies
Some of the key companies in the Mesothelioma Therapeutics Market include:
Key companies developing therapies for Mesothelioma are – Merck & Co., Inc., Bristol-Myers Squibb, AstraZeneca, Roche, Novartis, Pfizer Inc., Eli Lilly and Company, Johnson & Johnson, GlaxoSmithKline plc (GSK), AbbVie Inc., Sanofi, and others.
Mesothelioma Pipeline Analysis:
The Mesothelioma pipeline report provides insights into
The report provides detailed insights about companies that are developing therapies for the treatment of Mesothelioma with aggregate therapies developed by each company for the same.
It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Mesothelioma Treatment.
Mesothelioma key companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
Mesothelioma Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.
Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Mesothelioma market.
The report is built using data and information traced from the researcher’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations, and featured press releases from company/university websites and industry-specific third-party sources, etc.
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Mesothelioma Pipeline Market Drivers
Advancements in Treatment, Targeted Therapies, Immunotherapy Innovations, Early Diagnosis Initiatives, Increased Awareness, are some of the important factors that are fueling the Mesothelioma Market.
Mesothelioma Pipeline Market Barriers
However, Limited Treatment Option, Diagnostic Challenges, High Development Costs, Patient Heterogeneity, Lack of Funding, and other factors are creating obstacles in the Mesothelioma Market growth.
Scope of Mesothelioma Pipeline Drug Insight
Coverage: Global
Key Mesothelioma Companies: The Netherlands Cancer Institute, Bristol-Myers Squibb, PrECOG, LLC., Memorial Sloan Kettering Cancer Center, ETOP IBCSG Partners Foundation, MedImmune LLC, Åslaug Helland, AstraZeneca, Oncotelic Inc., Hyogo Medical University, Trizell Ltd, RS Oncology LLC, Vivace Therapeutics, Inc, TCR2 Therapeutics, Sanofi, ImmVira Pharma Co. Ltd, TCR2 Therapeutics, CRISPR Therapeutics, Biotheus Inc., and others
Key Mesothelioma Therapies: Pembrolizumab, Nivolumab, Durvalumab, Sacituzumab govitecan-hziy, Carboplatin, Tremelimumab, ipilimumab, Volrustomig, OT-101, Lenvatinib, rAd-IFN, RSO-021, VT3989, gavo-cel, THOR-707, T3011, TC-510, CTX131, PM8002, and others
Mesothelioma Therapeutic Assessment: Mesothelioma current marketed and Mesothelioma emerging therapies
Mesothelioma Market Dynamics: Mesothelioma market drivers and Mesothelioma market barriers
Request for Sample PDF Report for Mesothelioma Pipeline Assessment and clinical trials
Table of Contents
1. Mesothelioma Report Introduction
2. Mesothelioma Executive Summary
3. Mesothelioma Overview
4. Mesothelioma- Analytical Perspective In-depth Commercial Assessment
5. Mesothelioma Pipeline Therapeutics
6. Mesothelioma Late Stage Products (Phase II/III)
7. Mesothelioma Mid Stage Products (Phase II)
8. Mesothelioma Early Stage Products (Phase I)
9. Mesothelioma Preclinical Stage Products
10. Mesothelioma Therapeutics Assessment
11. Mesothelioma Inactive Products
12. Company-University Collaborations (Licensing/Partnering) Analysis
13. Mesothelioma Key Companies
14. Mesothelioma Key Products
15. Mesothelioma Unmet Needs
16 . Mesothelioma Market Drivers and Barriers
17. Mesothelioma Future Perspectives and Conclusion
18. Mesothelioma Analyst Views
19. Appendix
20. About DelveInsight
About DelveInsight
DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance. It also offers Healthcare Consulting Services, which benefits in market analysis to accelerate business growth and overcome challenges with a practical approach.
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