“Down Syndrome Pipeline Insight, 2024“ report by DelveInsight outlines comprehensive insights into the present clinical development scenario and growth prospects across the Down Syndrome Market.
The Down Syndrome Pipeline report embraces in-depth commercial and clinical assessment of the pipeline products from the pre-clinical developmental phase to the marketed phase. The report also covers a detailed description of the drug, including the mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, collaborations, mergers acquisition, funding, designations, and other product-related details.
Some of the key takeaways from the Down Syndrome Pipeline Report:
Companies across the globe are diligently working toward developing novel Down Syndrome treatment therapies with a considerable amount of success over the years.
Down Syndrome companies working in the treatment market are Aelis Farma, AC Immune SA, Eisai Inc., Forest Laboratories, Eisai Co., Hoffmann-La Roche, Elan Pharma, Life Molecular Imaging, Cidara Therapeutics, and others, are developing therapies for the Down Syndrome treatment
Emerging Down Syndrome therapies in the different phases of clinical trials are- AEF0217, ACI-24.060, Donepezil HCl, Memantine, E2020, RG1662, ELND005, Florbetaben (BAY94-9172), CD101, and others are expected to have a significant impact on the Down Syndrome market in the coming years.
In December 2024, AC Immune SA (NASDAQ: ACIU), a clinical-stage biopharmaceutical company at the forefront of developing precision therapeutics for neurodegenerative diseases, has released interim safety and tolerability data from the ABATE Phase 1b/2 trial of ACI-24.060 in individuals with Down syndrome. ACI-24.060 is an active immunotherapy targeting toxic forms of amyloid beta (Abeta) 1-15, excluding Abeta T-cell epitopes. The interim analysis, based on data from the first two cohorts receiving low-dose and mid-dose ACI-24.060, showed that participants have been treated for up to one year with no serious adverse events related to the drug and no cases of amyloid-related imaging abnormalities (ARIA) in this population.
In November 2024, Aelis Farma (ISIN: FR0014007ZB4 – AELIS), a clinical-stage biopharmaceutical company focused on developing treatments for brain and peripheral diseases related to the CB1 receptor, has announced positive results from a Phase 1/2 clinical trial of AEF02171 in young adults with Down syndrome.
Down Syndrome Overview
Down Syndrome is a genetic condition caused by the presence of an extra copy of chromosome 21, also known as trisomy 21. This condition affects physical growth, cognitive development, and often leads to characteristic facial features, such as a flat facial profile and almond-shaped eyes. Individuals with Down Syndrome may experience varying degrees of intellectual disability and are at an increased risk for certain medical conditions, including heart defects, thyroid issues, and hearing problems. While there is no cure, supportive care, early intervention, and educational programs can help individuals lead fulfilling lives.
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Emerging Down Syndrome Drugs Under Different Phases of Clinical Development Include:
AEF0217: Aelis Farma
ACI-24.060: AC Immune SA
Donepezil HCl: Eisai Inc.
Memantine: Forest Laboratories
E2020: Eisai Co., Ltd.
RG1662: Hoffmann-La Roche
ELND005: Elan Pharma
Florbetaben (BAY94-9172): Life Molecular Imaging
CD101: Cidara Therapeutics
Down Syndrome Route of Administration
Down Syndrome pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs, such as
Oral
Parenteral
Intravenous
Subcutaneous
Topical
Down Syndrome Molecule Type
Down Syndrome Products have been categorized under various Molecule types, such as
Monoclonal Antibody
Peptides
Polymer
Small molecule
Gene therapy
Down Syndrome Pipeline Therapeutics Assessment
Down Syndrome Assessment by Product Type
Down Syndrome By Stage and Product Type
Down Syndrome Assessment by Route of Administration
Down Syndrome By Stage and Route of Administration
Down Syndrome Assessment by Molecule Type
Down Syndrome by Stage and Molecule Type
DelveInsight’s Down Syndrome Report covers around 5+ products under different phases of clinical development like
Late-stage products (Phase III)
Mid-stage products (Phase II)
Early-stage product (Phase I)
Pre-clinical and Discovery stage candidates
Discontinued & Inactive candidates
Route of Administration
Further Down Syndrome product details are provided in the report. Download the Down Syndrome pipeline report to learn more about the emerging Down Syndrome therapies
Some of the key companies in the Down Syndrome Therapeutics Market include:
Key companies developing therapies for Down Syndrome are – Biogen Inc., Axsome Therapeutics Inc., F. Hoffmann-La Roche Ltd., Eli Lilly and Company, and others.
Down Syndrome Pipeline Analysis:
The Down Syndrome pipeline report provides insights into
The report provides detailed insights about companies that are developing therapies for the treatment of Down Syndrome with aggregate therapies developed by each company for the same.
It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Down Syndrome Treatment.
Down Syndrome key companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
Down Syndrome Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.
Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Down Syndrome market.
The report is built using data and information traced from the researcher’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations, and featured press releases from company/university websites and industry-specific third-party sources, etc.
Download Sample PDF Report to know more about Down Syndrome drugs and therapies
Down Syndrome Pipeline Market Drivers
Growing Awareness and Early Diagnosis, Advancements in Medical Research, Government Support and Initiatives, Rising Demand for Specialized Therapies, Enhanced Education and Social Inclusion Programs, are some of the important factors that are fueling the Down Syndrome Market.
Down Syndrome Pipeline Market Barriers
However, Limited Treatment Options, High Healthcare Costs, Low Awareness in Certain Regions, Stigma and Social Challenges, Ethical and Regulatory Challenges, and other factors are creating obstacles in the Down Syndrome Market growth.
Scope of Down Syndrome Pipeline Drug Insight
Coverage: Global
Key Down Syndrome Companies: Aelis Farma, AC Immune SA, Eisai Inc., Forest Laboratories, Eisai Co., Hoffmann-La Roche, Elan Pharma, Life Molecular Imaging, Cidara Therapeutics, and others
Key Down Syndrome Therapies: AEF0217, ACI-24.060, Donepezil HCl, Memantine, E2020, RG1662, ELND005, Florbetaben (BAY94-9172), CD101, and others
Down Syndrome Therapeutic Assessment: Down Syndrome current marketed and Down Syndrome emerging therapies
Down Syndrome Market Dynamics: Down Syndrome market drivers and Down Syndrome market barriers
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Table of Contents
1. Down Syndrome Report Introduction
2. Down Syndrome Executive Summary
3. Down Syndrome Overview
4. Down Syndrome- Analytical Perspective In-depth Commercial Assessment
5. Down Syndrome Pipeline Therapeutics
6. Down Syndrome Late Stage Products (Phase II/III)
7. Down Syndrome Mid Stage Products (Phase II)
8. Down Syndrome Early Stage Products (Phase I)
9. Down Syndrome Preclinical Stage Products
10. Down Syndrome Therapeutics Assessment
11. Down Syndrome Inactive Products
12. Company-University Collaborations (Licensing/Partnering) Analysis
13. Down Syndrome Key Companies
14. Down Syndrome Key Products
15. Down Syndrome Unmet Needs
16 . Down Syndrome Market Drivers and Barriers
17. Down Syndrome Future Perspectives and Conclusion
18. Down Syndrome Analyst Views
19. Appendix
20. About DelveInsight
About DelveInsight
DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance. It also offers Healthcare Consulting Services, which benefits in market analysis to accelerate business growth and overcome challenges with a practical approach.
Media ContactCompany Name: DelveInsight Business Research LLPContact Person: Shruti ThakurEmail: Send EmailPhone: 09650213330Address:304 S. Jones Blvd #2432 City: Las VegasState: NVCountry: United StatesWebsite: https://www.delveinsight.com/
