DelveInsight’s “Nephrotic Syndrome Market Insights, Epidemiology, and Market Forecast–2034” report delivers an in-depth understanding of the Nephrotic Syndrome, historical and forecasted epidemiology, and the Nephrotic Syndrome market trends in the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan.

 

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Key Takeaways from the Nephrotic Syndrome Market Report

• In January 2025:- Hoffmann-La Roche- A Phase III, International, Multicenter, Randomised Open Label Study to Evaluate the Efficacy and Safety of Obinutuzumab Versus MMF in Patients With Childhood Onset Idiopathic Nephrotic Syndrome. This open-label, randomized multicenter study is to assess the efficacy, safety, and pharmacokinetics (PK)/pharmacodynamics (PD) of obinutuzumab compared with mycophenolate mofetil (MMF) in children and young adults (aged >= 2-25 years) with frequently relapsing nephrotic syndrome (FRNS) or steroid-dependent nephrotic syndrome (SDNS).
• As per DelveInsight’s estimations, the total Nephrotic Syndrome diagnosed prevalent cases in the 7MM were approximately 786k in 2022 and are projected to increase during the forecast period.
• The overall count of individuals diagnosed with Nephrotic Syndrome in the United States was approximately 268k in 2022, and it is expected to increase at an estimated CAGR throughout the study period (2020–2034).
• Among the 7MM, the US accounted for nearly 214k cases of Primary Glomerulonephropathies, and 54k cases of Secondary Glomerulonephropathies. These cases are expected to increase during the forecast period (2023–2034).
• Among EU4 and the UK, Germany had the highest Nephrotic Syndrome diagnosed prevalent population, with about 98k cases, followed by the UK and France in 2022. On the other hand, Spain had the lowest diagnosed prevalent population in EU4 and the UK in 2022.
• In Japan, there were around 151k Nephrotic Syndrome diagnosed prevalent cases in 2022. These cases are expected to decrease by 2032.
• The leading Nephrotic Syndrome Companies such as Vertex Pharmaceuticals, Chinook Therapeutics, Novartis, Boehringer Ingelheim, Hoffmann-La Roche, Biogen, Cerium Pharmaceuticals, Otsuka Pharmaceutical Development & Commercialization, Visterra, Ionis Pharmaceuticals, Kezar Life Sciences, Alpine Immune Sciences, Dimerix Bioscience, Advanz Pharma, Apellis Pharmaceuticals, Vera Therapeutics, Inc., AstraZeneca, and others.
• Promising Nephrotic Syndrome Therapies such as Mizoribine (MZR), Cyclophosphamide (CTX), Obinutuzumab, Prednisone, Tacrolimus, and others.

 

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Nephrotic Syndrome Epidemiology Segmentation in the 7MM

• Total Nephrotic Syndrome Diagnosed Prevalent Cases
• Nephrotic Syndrome Type-specific Diagnosed Prevalent Cases

 

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Nephrotic Syndrome Emerging Drugs

• Atacicept: Vera Therapeutics

Atacicept developed by Vera Therapeutics, is an investigational recombinant fusion protein that contains the soluble transmembrane activator and calcium-modulating cyclophilin ligand interactor (TACI) receptor that binds to the cytokines B lymphocyte stimulator (BLyS) and a proliferation-inducing ligand (APRIL). These cytokines are members of the tumor necrosis factor family that promote B-cell survival and autoantibody production associated with certain autoimmune diseases, including IgA nephropathy and lupus nephritis.

 

• Atrasentan: Chinook Therapeutics/ Novartis

Atrasentan is an oral potent and selective endothelin A (ETA) receptor antagonist, which works by inhibiting the ETA receptor activation of multiple renal cell types. This blockade reduces kidney inflammation and fibrosis, thus leading to reduced proteinuria in patients with chronic kidney disease.

 

Nephrotic Syndrome Market Outlook

Nephrotic syndrome is a collection of symptoms that signal impaired kidney function. These symptoms encompass proteinuria, hypoalbuminemia, edema, hyperlipidemia, and various other associated complications of Nephrotic Syndrome. The management of nephrotic syndrome entails addressing underlying medical conditions contributing to its onset. Healthcare professionals may prescribe medications and dietary modifications to regulate symptoms and address complications of nephrotic syndrome.

 

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Nephrotic Syndrome Companies

Vertex Pharmaceuticals, Chinook Therapeutics, Novartis, Boehringer Ingelheim, Hoffmann-La Roche, Biogen, Cerium Pharmaceuticals, Otsuka Pharmaceutical Development & Commercialization, Visterra, Ionis Pharmaceuticals, Kezar Life Sciences, Alpine Immune Sciences, Dimerix Bioscience, Advanz Pharma, Apellis Pharmaceuticals, Vera Therapeutics, Inc., AstraZeneca, and others

 

Scope of the Nephrotic Syndrome Market Report

• Coverage- 7MM
• Study Period- 2020-2034
• Nephrotic Syndrome Companies- Vertex Pharmaceuticals, Chinook Therapeutics, Novartis, Boehringer Ingelheim, Hoffmann-La Roche, Biogen, Cerium Pharmaceuticals, Otsuka Pharmaceutical Development & Commercialization, Visterra, Ionis Pharmaceuticals, Kezar Life Sciences, Alpine Immune Sciences, Dimerix Bioscience, Advanz Pharma, Apellis Pharmaceuticals, Vera Therapeutics, Inc., AstraZeneca, and others
• Nephrotic Syndrome Therapies- Mizoribine (MZR), Cyclophosphamide (CTX), Obinutuzumab, Prednisone, Tacrolimus, and others.
• Nephrotic Syndrome Therapeutic Assessment: Nephrotic Syndrome current marketed and Nephrotic Syndrome emerging therapies
• Nephrotic Syndrome Market Dynamics: Nephrotic Syndrome market drivers and Nephrotic Syndrome market barriers
• Nephrotic Syndrome Unmet Needs, KOL’s views, Analyst’s views, Nephrotic Syndrome Market Access and Reimbursement

 

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Table of Content

1. Key Insights

2. Report Introduction

3. Nephrotic Syndrome Market Overview at a Glance

4. Epidemiology and Market Methodology of Nephrotic Syndrome

5. Executive Summary of Nephrotic Syndrome

6. Key Events

7. Nephrotic Syndrome: Disease Background and Overview

8. Epidemiology and Patient Population

9. Patient Journey

10. Marketed Drugs

11. Emerging Therapies

12. Nephrotic Syndrome: Seven Major Market Analysis

13. KOL Views

14. SWOT Analysis

15. Unmet Needs

16. Market Access and Reimbursement

17. Appendix

18. DelveInsight Capabilities

19. Disclaimer

 

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