DelveInsight’s “Axial Spondyloarthritis Market Insights, Epidemiology and Market Forecast–2034” report delivers an in-depth understanding of the indication axial spondyloarthritis, historical and forecasted epidemiology as well as the axial spondyloarthritis market trends in the United States, EU4 (Germany, Spain, Italy, and France) and the United Kingdom, and Japan.

 

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Key Takeaways from the Axial Spondyloarthritis Market Report

• In November 2024:- UCB Biopharma SRL- A Multicenter, Open-Label Extension Study to Asses the Long-Term Safety, Tolerability, and Efficacy of Bimekizumab in the Treatment of Study Participants With Active Axial Spondyloarthritis, Ankylosing Spondylitis, and Nonradiographic Axial Spondyloarthritis. The purpose of the study is to demonstrate the long-term safety, tolerability and efficacy of bimekizumab in patients with active axial spondyloarthritis (axSpA, also known as radiographic axSpa (r-axSpA)) including ankylosing spondylitis (AS) and nonradiographic axial spondyloarthritis (nr-axSpa).
• As per DelveInsight’s estimates, the total diagnosed population of non-radiographic axial spondyloarthritis in the US was around 569,000 cases in 2023.
• Among EU4 and UK countries, Germany had the highest number of prevalent axial spondyloarthritis cases in 2023, followed by Spain.
• The leading Axial Spondyloarthritis Companies such as Janssen Pharmaceuticals, Pfizer, UCB Biopharma, Celgene, Inmagene Biopharmaceuticals, Galapagos NV, Kyowa Kirin Co., Ltd., Eli Lilly and Company, Merck Sharp & Dohme LLC, Pfizer, Novartis, Jiangsu HengRui Medicine, UCB Biopharma, and others
• Promising Axial Spondyloarthritis Therapies such as SIMPONI (golimumab), XELJANZ (tofacitinib), Bimekizumab, CC-99677, ABY- 035, Filgotinib, KHK4827, Ixekizumab, Golimumab, etanercept, Secukinumab, SHR0302, Certolizumab Pegol, and others

 

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Axial Spondyloarthritis Epidemiology Segmentation in the 7MM

• Total Axial Spondyloarthritis Prevalent Cases
• Total Axial Spondyloarthritis Diagnosed Prevalent Cases
• Axial Spondyloarthritis Gender-specific Cases
• Axial Spondyloarthritis Gene-specific Cases
• Axial Spondyloarthritis Age-specific Cases
• Total Axial Spondyloarthritis Treated Cases

 

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 Axial Spondyloarthritis Marketed Drugs

• SIMPONI (golimumab): Janssen Pharmaceuticals

SIMPONI is a human IgG1? monoclonal antibody specific for human tumor necrosis factor-alpha (TNF–-a) that exhibits multiple glycoforms. It was created using genetically engineered mice immunized with human TNF, resulting in an antibody with human-derived antibody variable and constant regions. It binds to both the soluble and transmembrane bioactive forms of human TNFa. This interaction prevents the binding of TNFa to its receptors, thereby inhibiting the biological activity of TNFa (a cytokine protein). This molecule is produced by a recombinant cell line cultured by continuous perfusion and is purified by a series of steps that include measures to inactivate and remove viruses.

 

• XELJANZ (tofacitinib): Pfizer

XELJANZ, a film-coated immediate-release tablet, is the first and only oral JAK inhibitor approved in the European Union for five indications. It is prescribed for adults with active AS who have not responded adequately to conventional therapy and for adults with moderately to severely active RA after failure or intolerance to disease-modifying antirheumatic drugs (DMARDs). Additionally, it is used for adults with active PsA after DMARD failure or intolerance and for adults with moderately to severely active UC who have had an inadequate response, lost response, or were intolerant to conventional therapy or a biologic agent.

 

Axial Spondyloarthritis Market Outlook

The market size of axial spondyloarthritis in the seven major markets is expected to increase substantially from 2024. The United States accounts for the largest market size of axial spondyloarthritis, in comparison to EU4 (Germany, Spain, Italy, France), the United Kingdom, and Japan. Among EU4 and the UK, Germany has the largest market size, followed by Spain, with France having the smallest market size. In 2023, the total market size for axial spondyloarthritis therapies was approximately USD 9 million, with the majority occupied by conventional treatments.

 

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Axial Spondyloarthritis Therapies and Companies

• SIMPONI (golimumab): Janssen Pharmaceuticals
• XELJANZ (tofacitinib): Pfizer
• Bimekizumab: UCB Biopharma
• CC-99677: Celgene
• ABY- 035: Inmagene Biopharmaceuticals
• Filgotinib: Galapagos NV
• KHK4827: Kyowa Kirin Co., Ltd.
• Ixekizumab: Eli Lilly and Company
• Golimumab: Merck Sharp & Dohme LLC
• etanercept: Pfizer
• Bimekizumab: UCB Biopharma
• Secukinumab: Novartis
• SHR0302: Jiangsu HengRui Medicine
• Certolizumab Pegol: UCB Biopharma

 

Axial Spondyloarthritis Market Drivers

• The introduction of novel products
• Increasing prevalence
• Awareness about the Disease
• Research and development strategies

 

Axial Spondyloarthritis Market Barriers

• High-cost treatment
• Delay in Diagnosis
• Immunogenicity
• Loss of patent exclusivity
• Availability of generics
• Poor Quality of Life

 

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Scope of the Axial Spondyloarthritis Market Report

• Coverage- 7MM
• Axial Spondyloarthritis Companies- Janssen Pharmaceuticals, Pfizer, UCB Biopharma, Celgene, Inmagene Biopharmaceuticals, Galapagos NV, Kyowa Kirin Co., Ltd., Eli Lilly and Company, Merck Sharp & Dohme LLC, Pfizer, Novartis, Jiangsu HengRui Medicine, UCB Biopharma, and others
• Axial Spondyloarthritis Therapies- SIMPONI (golimumab), XELJANZ (tofacitinib), Bimekizumab, CC-99677, ABY- 035, Filgotinib, KHK4827, Ixekizumab, Golimumab, etanercept, Secukinumab, SHR0302, Certolizumab Pegol, and others.
• Axial Spondyloarthritis Therapeutic Assessment: Axial Spondyloarthritis Current marketed and Lipodystrophy Emerging Therapies
• Axial Spondyloarthritis Market Dynamics: Axial Spondyloarthritis Market drivers and Lipodystrophy Market Barriers

 

Table of Content

1. Key Insights

2. Report Introduction

3. Axial Spondyloarthritis (axSpA) Market Overview at a Glance

4. Methodology

5. Executive Summary

6. Disease Background and Overview

7. Treatment of Axial Spondyloarthritis (axSpA)

8. Epidemiology and Patient Population

9. Patient Journey

10. Marketed Therapies

11. Market Analysis

12. KOL Views

13. SWOT Analysis

14. Unmet Needs

15. Market Access and Reimbursement

16. Appendix

17. DelveInsight Capabilities

18. Disclaimer

 

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